Laboratory for Stem Cells and Regenerative Biomedical Engineering

Dr. Kisuk Yang works in the fields of medical devices, stem cell and tissue engineering. His laboratory focuses on the design and testing of bioengineered tissues, which are composed of mainly stem cell-derived cells (e.g., neural cells, pancreatic cells, and osteogenic cells) and tissue-specific extracellular matrix scaffolds. The overall goal is to develop new strategies to assemble and test bioengineered constructs capable of restoring tissue function. 

 

The major goals of the laboratory are i) to harness the power of stem cell niches (e.g., 3D microenvironment, ECM, cell-cell interaction, and cell signaling) to guide stem cell differentiation and/or tissue remodeling in vitro and in vivo, and ii) to understand and harness the interaction between inflammatory cells and bioengineered tissue constructs in order to improve survival and function.